Exogenous Ethyl Pyruvate versus Pyruvate during Metabolic Recovery after Oxidative Stress in Neonatal Rat Cerebrocortical Slices
نویسندگان
چکیده
منابع مشابه
Attenuation of Methotrexate-Induced Embryotoxicity and Oxidative Stress by Ethyl Pyruvate
Objective Methotrexate (MTX), as an anti-folate agent, is widely used in the treatment of rheumatic disorders and malignant tumors, however it damages reproductive system in mice. The aim of this research was to study the effects of ethyl pyruvate (EP) on embryo development and oxidative stress changes in the testis of mice treated with MTX. MaterialsAndMethods In this experimental study, thirt...
متن کاملattenuation of methotrexate-induced embryotoxicity and oxidative stress by ethyl pyruvate
objective: methotrexate (mtx), as an anti-folate agent, is widely used in the treatment of rheumatic disorders and malignant tumors, however it damages reproductive system in mice. the aim of this research was to study the effects of ethyl pyruvate (ep) on embryo development and oxidative stress changes in the testis of mice treated with mtx. materials and methods: in this experimental study, t...
متن کاملEthyl pyruvate treatment mitigates oxidative stress damage in cultured trabecular meshwork cells
PURPOSE Oxidative stress plays a key role in the pathophysiology of glaucoma. This study was designed to assess ethyl pyruvate (EP) as a novel antioxidative agent in cultured human trabecular meshwork (hTM) cells. METHODS Primary hTM cells were cultured on collagen matrices. Tolerance to EP was assessed at various concentrations using fluorescent vital dyes (live/dead) and metabolic (1-(4,5-d...
متن کاملprotective effect of ethyl pyruvate on epididymal sperm characteristics, oxidative stress and testosterone level in methotrexate treated mice
background: methotrexate (mtx) is an anti-metabolite drug widely used in treatment of neoplastic disorders, rheumatoid arthritis and psoriasis. the ester derivative, ethyl pyruvate (ep) is stable in solution and should function as an antioxidant and energy precursor. this study was conducted to evaluate the protective role of ep on sperm parameters, testosterone level and malondialdehyde (mda) ...
متن کاملAttenuation of Methotrexate-Induced Embryotoxicity and Oxidative Stress by Ethyl Pyruvate
BACKGROUND Methotrexate (MTX), as an anti-folate agent, is widely used in the treatment of rheumatic disorders and malignant tumors, however it damages reproductive sys- tem in mice. The aim of this research was to study the effects of ethyl pyruvate (EP) on embryo development and oxidative stress changes in the testis of mice treated with MTX. MATERIALS AND METHODS In this experimental study...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2007
ISSN: 0003-3022
DOI: 10.1097/01.anes.0000281898.01966.1e